True
Space Available For Lease 1
2nd Floor |
The entire second floor has a current buildout for a dental office with a mix of offices and exam rooms — ideal for dentistry, medical spa, chiropractic, and other wellness practices. or professional office uses. Current tenants on the first floor provide hair, skincare, massage, and therapy services. ![]()
Lida Eberz
CBRE ![]()
Tom Roberts
CBRE |
Contacts

CBRE

CBRE
Property Details
- Property Type Office - Medical Office
- Property Size 4,400 SF
- Lot Size 0.51 Acre
- Parking Spaces Avail. 15
- Parking Ratio 3.41 / 1,000 SF
- Building Class C
- Year Built 1972
- Date Updated Mar 24, 2025
±15 parking spaces
High visibility location (17,637 AADT) with monument signage
Monument signage
Nearby highway access - minutes to I-90, Rt. 219, and Rt. 400
Reach out to the broker for more info on lease terms and amenities
Getting around
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Walk Score ®
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Bike Score ®
Location
- City Buffalo, NY
- Zip Code 14224
- Market Buffalo
Points of Interest
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Southgate Plaza
0.56 miles
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Abbott Bailey Loop
4.71 miles
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Buffalo–Exchange Street Station
7.41 miles
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Canalside
7.51 miles
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Lafayette Square
7.73 miles
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Metro Rail Station
8.13 miles
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Humboldt–Hospital
9.01 miles
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Hertel & Voorhees
9.94 miles
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Hertel & Vorrhees
9.95 miles
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University Station
9.97 miles
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Sunoco
1.35 miles
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Express Mart and Tim Hortons
1.42 miles
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Delta Sonic
1.55 miles
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Tops
1.55 miles
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Mobil
2.46 miles
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Speedway
3.46 miles
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Tesla Supercharger
3.72 miles
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ChargePoint
9.88 miles
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West Seneca Municipal Parking
2.53 miles
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Mangia Restaurnt parking
3.60 miles
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DeLacy Ford
3.62 miles
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Town Hall parking
3.71 miles
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Orchard Park Middle School Parking
3.73 miles
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Lot 2 ADA
3.75 miles
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Orchard Presbyterian Church parking lot
3.88 miles
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Lot G
3.90 miles
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Nativity of our Lord Church parking lot
3.90 miles
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Lot 1
3.91 miles
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Hampton Inn & Suites
2.00 miles
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Country Inn & Suites, Buffalo South I-90
2.16 miles
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Staybridge Suites
2.20 miles
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Econo Lodge Buffalo South
3.88 miles
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Best Western Plus Galleria Inn & Suites
4.52 miles
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Quality Inn Near Walden Galleria Mall
4.63 miles
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La Quinta Inn & Suites Lackawanna
4.74 miles
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Home2 Suites by Hilton Buffalo Airport/Galleria Mall
5.99 miles
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Holiday Inn Express Cheektowaga North East
6.10 miles
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Baymont Buffalo
6.13 miles
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The Market in the Square
0.48 miles
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Big Lots
1.55 miles
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Tops
1.66 miles
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ALDI
1.68 miles
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Wegmans
1.93 miles
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Marshalls
2.42 miles
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Target
2.45 miles
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Kohl's
2.52 miles
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Save-A-Lot
3.00 miles
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McKinley Mall
3.74 miles
721 Union Rd Listing Brief
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Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 721 Union Rd has to offer.
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The property offers a parking ratio of 3.41 / 1,000 SF, which translates to a total of 15 parking spaces. See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.
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721 Union Rd was originally completed in 1972 and is rated class C. The building includes 4,400 square feet, of which 2,200 square feet is rentable office space.
Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.