Innovation Square

For Lease

2220 E 105th St, Cleveland, OH 44010

There is currently one space available at Innovation Square. The building’s general use is vacantland. The space listed for lease is described as vacantland. Current availability totals 30,492 square feet. Of this, minimum divisible area is 0.7 square feet. The listed lease rate is contact for pricing.

Space Available For Lease 1

Contacts

broker
Hanna Trolli

Passov Real Estate Group

Property Details

  • Property Type VacantLand
  • Lot Size 0.7 Acre
  • Date Updated Apr 21, 2025
This highly visible development site lies within Cleveland’s transformative Opportunity Corridor, connecting I-490 to University Circle through the heart of the Fairfax neighborhood. The site—just steps from the Cleveland Clinic Main Campus—is surrounded by public and private investments reshaping the area into a hub for innovation, healthcare, and mixed-use development. Nearby residential projects like Axis at Ansel (163 units) and Innova (177 units) support a growing, walkable community. Additionally, the property is within walking distance to the new Fairfax Meijer, a full-service grocery and neighborhood anchor.
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Highlights

  • .70 AC available for ground lease or sale within the Opportunity Corridor
  • Potential to expand assemblage
  • Prime land assemblage with visibility and access
  • Adjacent to Cleveland Clinic Main Campus and walking distance to Fairfax Meijer, Medley Apartments, and Saucy Brew Works
  • Surrounded by over 700+ apartment unites within a 1/2 mile radius, including Medley, Axis at Ansel, Aura at Innovation Square, and Skyline on Stokes
  • Less than 1 mile from Case Western Reserve University and University Circle

Getting around

  • 55/100

    Walk Score ®

  • 59/100

    Transit Score ®

  • 45/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Cleveland, OH
  • Neighborhood Fairfax
  • Zip Code 44010
  • Market Cleveland Akron

Points of Interest

  • Buckeye–Woodhill

    1.04 miles

  • East 79th

    1.49 miles

  • Coventry

    1.89 miles

  • Superior

    2.16 miles

  • East 55th

    2.23 miles

  • Stokes-Windermere Station

    2.78 miles

  • South Harbor

    3.85 miles

  • East 9th–North Coast

    4.11 miles

  • Cleveland Amtrak

    4.22 miles

  • Settlers Landing

    4.40 miles

  • Prestige Petrol

    0.89 miles

  • Sunoco

    0.94 miles

  • Fuel Point

    1.10 miles

  • Get Go

    1.15 miles

  • Gas USA

    1.36 miles

  • BP

    1.48 miles

  • Valero

    1.76 miles

  • Shell

    1.78 miles

  • Ohio Gas

    1.83 miles

  • South-East Harley Davidson

    7.53 miles

  • Cleveland Clinic Parking (P2) - Skyway access on level 3

    0.24 miles

  • W. O. Walker Center Garage

    0.35 miles

  • VISITOR LOT Lot S-63

    0.60 miles

  • Cleveland Clinic Parking (P1) - Elevators On SE Corner - Pedestrian Tunnel On Basement (B) Level

    0.61 miles

  • Underground and Surface Parking

    0.61 miles

  • Guest Parking 10 min.

    0.61 miles

  • Lot 13

    0.64 miles

  • Veale Center Parking Garage

    0.64 miles

  • SP+ Lot 82

    0.67 miles

  • UH Parking Garage

    0.67 miles

  • Tudor Arms Hotel

    0.26 miles

  • InterContinental Hotel Cleveland

    0.34 miles

  • Residence Inn

    0.60 miles

  • InterContinental Suites Hotel Cleveland

    0.62 miles

  • Holiday Inn Cleveland Clinic

    0.68 miles

  • Courtyard Cleveland University Circle

    0.90 miles

  • Glidden House

    1.02 miles

  • The Lancer

    1.05 miles

  • Tru by Hilton

    1.44 miles

  • Star's Compound

    2.30 miles

  • Meijer

    0.09 miles

  • Simon's

    1.04 miles

  • Plum Market

    1.07 miles

  • ALDI

    1.17 miles

  • Dave's Supermarket

    1.61 miles

  • Dave's

    1.76 miles

  • Save-A-Lot

    1.88 miles

  • 5th Street Arcades

    3.82 miles

  • Galleria at Erieview

    3.88 miles

  • Burlington

    3.97 miles

In-Depth Research Available for this Property

Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.

Contact Listing Broker
broker
Hanna Trolli

Passov Real Estate Group

  1. 1Main information
  2. 2Extra information
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