421 W 2nd St

For Sale

421 W 2nd St, Defiance, OH 43512

This Defiance property for sale is located at 421 W 2nd St. The general use of 421 W 2nd St is office and it incorporates 2,736 square feet of class A office space. The current listed sale price for 421 W 2nd St is $325,000. 421 W 2nd St is situated on a lot that is 0.11 acre in size.

Contacts

broker
Stephanie Kuhlman

NAI Harmon Group

Property Details

  • Property Type Office - General Office
  • Property Size 2,736 SF
  • Lot Size 0.11 Acre
  • Building Class A
  • Year Built 1949
  • Date Updated Apr 14, 2025
421 W. 2nd St. is a 0.20 acre commercial lot with an existing 2,736 ± SF building, located just west of downtown Defiance. Positioned along W. 2nd St., the site offers strong local visibility and convenient access for a range of business types. The property is surrounded by a mix of residential neighborhoods and established commercial users. Nearby retailers and services include CVS, Family Dollar, Sherwin-Williams, Rite Aid, Kroger, and various restaurants, auto shops, and gas stations. Traffic along W. 2nd St. benefits from consistent daily volumes, with additional flow driven by nearby Clinton St. (OH-66), one of Defiance’s primary commercial corridors. The location is approximately 1.5 miles from U.S. Route 24, providing quick expressway access to Toledo, Fort Wayne, and surrounding markets. State Route 15 is also close by, enhancing regional connectivity. Zoned for commercial use by the City of Defiance, the property is suitable for retail, service, office, or redevelopment opportunities.421 W. 2nd St. offers a commercial opportunity just west of downtown Defiance. This 2,340± SF freestanding building sits on a 0.20 acre lot with frontage on W. 2nd St., a well-traveled corridor connecting residential neighborhoods with the city center.
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Highlights

  • 2,340± SF Building
  • 0.20 Acres
  • Zoned Commercial (City of Defiance)
  • Off-Street Parking
  • Minutes to US-24 and OH-15
  • Surrounded by national retailers and neighborhood traffic

Getting around

  • 59/100

    Walk Score ®

  • 53/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Defiance, OH
  • Zip Code 43512

Points of Interest

  • Speedway

    1.34 miles

  • Marathon Gas - Newman's Carryout

    1.65 miles

  • Meijer Gas Station

    1.68 miles

  • Hampton Inn

    1.62 miles

  • Quality Inn

    1.65 miles

  • Holiday Inn Express

    1.74 miles

  • La Jaliscience

    0.53 miles

  • ALDI

    0.95 miles

  • Chief's Supermarket

    1.10 miles

  • Big Lots

    1.17 miles

  • Walmart Supercenter

    1.37 miles

  • Meijer

    1.69 miles

  • Kroger

    1.70 miles

  • Kohl's

    2.12 miles

In-Depth Research Available for this Property

Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.

Contact Listing Broker
broker
Stephanie Kuhlman

NAI Harmon Group

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