UCSF Opens $228M Health-Care Facility

Construction of the five-story building started in 2021.

Exterior of Bayfront Medical Building in San Francisco
The 181,000-square-foot Bayfront Medical Building includes 14 operating rooms and 15 kinds of specialty care. Image by Barbara Ries, courtesy of UCSF

UCSF Health opens today Bayfront Medical Building, a 181,000-square-foot outpatient clinic, at its Mission Bay medical campus in San Francisco. The project’s development costs amounted to $228 million, San Francisco Chronicle reported.

Clark Construction Group broke ground on the five-story building in September 2021. The development team also included Stantec, Rutherford + Chekene and Guttmann & Blaevoet, among others.

A few months later, a nine-level garage started to rise nearby, meant to provide 500 car parking spaces for the new clinic. That structure came online in 2023.


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Bayfront Medical Building features 14 operating rooms for outpatient surgery, imaging suite, laboratory, physical and occupational therapy gym, 15 types of specialty care, as well as retail and pharmacy spaces. Its medical tenant roster includes the flagship UCSF Medical Center, UCSF Benioff Children’s Hospital, Langley Porter Psychiatric Hospital and Clinics and UCSF Faculty Practice, Becker’s Hospital Review reported.

The clinic will provide a variety of medical services, including allergy, dermatology, endocrinology, hepatology, pulmonology, urology, gastroenterology, pain medicine, physical therapy and rehabilitation and vascular surgery.

Formerly known as Block 34 Clinical Building, the facility is at 520 Illinois St., having access to Interstate 280 and public transportation. Downtown San Francisco is less than 3 miles away. Other medical providers in the surrounding area include Cardinal Medical Center and Concentra Urgent Care, among others.

Bay Area health-care development

As of August, the Bay Area had approximately 1.6 million square feet of medical office building space in various stages of development, CommercialEdge data shows.

One of the currently underway developments is Valley Health Center, a 230,000-square-foot medical office building in San Jose, Calif. Completion of the 10-story facility is expected in late 2025.

Planned projects include UCSF’s 284,800-square-foot research facility and outpatient treatment center in San Francisco. The facility would be part of the Potrero Power Station redevelopment district.